Hormone Therapy & Its Role Before/After Surgery: A Clinical Coordination Guide Hormone Therapy & Its Role Before/After Surgery: A Clinical Coordination Guide for Patients and Professionals 🩺 Executive Summary: Key Takeaways on Perioperative Hormone Management Navigating the intersection of hormone therapy and surgery requires careful, coordinated planning. Indeed, the decision to continue, pause, or initiate hormone treatment around a surgical procedure directly impacts safety, surgical success, and long-term health outcomes. Therefore, understanding the three primary contexts—oncology, gender-affirming care, and menopausal treatment—is essential. Oncology (Cancer Treatment): HT is often used as **Neoadjuvant** (before surgery to shrink tumors, as for some breast or prostate cancers) or **Adjuvant** (after surgery to prevent recurrence). Generally, patients should not interrupt this therapy without explicit surgical oncology and endocrinology coordination. Gender-Affirming Hormone Therapy (GAHT): For most **masculinizing** procedures, current guidelines suggest continuing GAHT. For many **feminizing** surgeries, particularly those with higher VTE (Venous Thromboembolism) risk like